Sometimes if the connection to a device via Minicom is lost, the next time you start Minicom you could see an error:

Device /dev/ttyS0 is locked.

The name /dev/ttyS0 may be different, depending on your COM port. To avoid this issue you should always shut down Minicom using CTRL+A keys and then the Q key.

To resolve the issue you can kill the process as a root user. Use the following command in your terminal:

killall -9 minicom

In Ubuntu is similar. Run the command in your terminal using sudo:

sudo killall -9 minicom

You can also try to delete the file:

LCK..ttyS0 in the /var/lock directory.

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